Patents and Funding


Patents: HOX11 Transgenic Mice. U.S. Application No.60/077,007. Application pending. (Rights assigned to: Sunnybrook & Women's College Health Sciences Centre.)

Growth Factors Genes. Canadian Patent Application #2,299,607 and United States Patent Application Pending. (Rights assigned to: Sunnybrook & Women's College Health Sciences Centre.)

Method and Product of Gene Transfer into Cells. U.S. Application No. 08/003,300, and Canadian Application No.2,096,844-9. Patent Pending. (Rights assigned to: University of Toronto Innovations Foundation.)

Funding: Total for 1986 through 2005 = $4,913,704
National Cancer Institute of Canada
2002 $133,405/yr 3yrs. (Co-investigator with M. Hough) Title: Pathogenesis of tumor progression in a transgenic mouse model for lymphoma.
1999 $110,639/yr 3 Years. (Principal investigator with M. Hough) Title: Pathogenesis of tumor progression in a transgenic mouse model for lymphoma.
1997 $156,413/yr 3 Years Operating Grant (Co-investigator with A.K. Stewart, A. Abrams-Ogg and S. Kruth) Title: MDR-1 transduced autologous marrow cells for chemoprotection in metastatic breast cancer.
1992 $121,694/yr 3 Years Operating Grant (Principal investigator with S. Kamel-Reid). Title: Characterization of HOX11: A new gene involved in human cancer.
Canadian Institutes for Health Research
(Medical Research Council of Canada)
2001 $50,000/yr 5 years (Network Center of Excellence). Title: Stem Cell Genomics and Therapeutic Network .
1998 $97,653/yr 4 years (Principal investigator with co-investigators S. Kruth and ACG Abrams - Ogg). Title: Gene therapy in a model system: Canine alpha-iduronidase deficiency.
1997 $45,528 Operating Grant (Principal investigator with co-investigators A.K. Stewart, S. Kruth, and ACG Abrams-Ogg). Title: Gene transfer into pluripotent hematopoietic progenitor cells.
1994 $94,000/yr 3 Years Operating Grant (Principal investigator with co-investigators S. Kamel-Reid, S. Kruth, and ACG Abrams-Ogg). Title: Gene transfer pluripotent hematopoietic progenitor cells.
1993 $30,000/yr 1 Year Operating Grant (Principal investigator with co-investigators S. Kamel-Reid, S. Kruth, and ACG Abrams-Ogg). Title: Gene transfer into pluripotent hematopoietic progenitor cells.
1990 $75,100/yr 3 Years Operating Grant (Principal investigator with co-investigators VEO Valli and S Kruth). Title: Canine model for autologous bone marrow transplantation using long-term bone marrow culture cells.
1989 $57,000/yr 3 Years Operating Grant (Principal investigator). Title: Cloning and characterization of the oncogene involved in the 10;14 translocation of T-cell neoplasia.
1988 $56,000/yr 2 Years Operating Grant (Principal investigator with co-investigators VEO Valli and S Kruth). Title: Canine model for autologous bone marrow transplantation using long-term bone marrow culture cells.
1996 $3,600 PMAC/MRC Studentship Grant (Tara Paton)
1995 $2,500 Symposium Grant (Gene Therapy in Canada)
1995 $3,500 Supervisor's Grant (David Allan)
1994 $3,500 Supervisor's Grant (David Allan)
1989 $1,300 Supervisor's Grant (Ron Carter)
1988 $1,300 Supervisor's Grant (Ron Carter)
1987 $1,300 Supervisor's Grant (Ron Carter)
Bayer Blood Partnership Fund
2000 $249,356 for 2 Years (Renewal application-Outcome Pending). (Principal investigator). Title: Molecular genetic characterization of the inductive hematopoietic microenvironment.
1998 $58,000/yr 2 Years Operating Grant. (Principal investigator). Title: Molecular genetic characterization of the inductive hematopoietic microenvironment.
University of Toronto
1987 $30,000 Faculty of Medicine, Excellence Award.
1986 $5,000 Dean's Fund Award.
Toronto General Hospital
1986 $13,000 Oncology Research, Start-up Fund
The Hospital For Sick Children Foundation
1994 $55,000/yr 2 Years Operating Grant (Principal investigator). Title: Gene therapy for human ADA-deficiency.
1990 $48,000/yr 2 Years Operating Grant (Principal investigator). Title: Molecular characterization of breakpoints in complex Philadelphia chromosomes.
1988 $50,000/yr 2 Years Operating Grant (Principal investigator). Title: Molecular characterization of the (10;14) translocation of childhood T-cell acute lymphoblastic leukemia.
Canadian Universities Research Program - Connaught Laboratories Ltd.
1994 $120,000/yr 3 Years Operating Grant (Principal investigator) . Title: A mouse model for human gene therapy.
The Banting Medical Research Foundation
1988 $10,000 Equipment Grant. Title: Cloning and characterization of the oncogene involved in the 10;14 translocation of T-cell neoplasia.
Somatix Therapy Corp.
1995 $57,876 Research Contract (Principal investigator). Title: Transduction of hematopoietic stem cells with the MFG virus carrying the human glucocerebrosidase gene.
Genetic Therapy Inc.
1996 $ 83,808 Research Contract (Principal Investigator) Title: Transfer of the MDR gene into hematopoietic stem cells.
Baxter (US) Gene Therapy Division.
1996 $448,500 Research Contract. (Co-investigator with K. Stewart, F. Graham, and J. Gauldie) Title: A phase II clinical trial of adenoviral mediated gene transfer of IL-2 cDNA into metastatic breast cancer and melanoma.
The Canadian Society for Mucopolysaccharide and Related Diseases Inc.
1996 $5,000 (Principal investigator with S. Kruth co-investigator). Title: Support for a canine MPS 1 colony.
Other Corporate Research Awards
1995 $27,350 Funding for Gene Therapy in Canada Conference. Donors include: Inex, Hemosol, Biochem, Glaxo, Genentech, Novopharm, Coopers & Lybrand, MDS Health Group, Allelix, Dalton, General Synthesis & Diagnostics Inc., Bayer, Scott & Aylen, Cansera, Eli Lilly, Toronto Biotechnology Initiative, Connaught, Imutec, Spectral Diagnostics Inc., Canadian Institute of Biotechnology, Medical Research Council.

Top Of Page